Perforin-2 (P2) is a pore-forming protein with cytotoxic activity against intracellular bacterial pathogens. P2 knockout (P2KO) mice are unable to control infections and die from normally non-lethal bacterial infections. Here we show that P2KO mice as compared to WT mice show significantly higher levels of systemic inflammation. measured by inflammatory markers in serum. https://www.rivervalleydanceac.com/product-category/3-piece-gift-set/
Impaired B Cell Function in Mice Lacking Perforin-2
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