Background Awake craniotomy is a well-tolerated procedure for the resection of brain tumors residing within or close to the eloquent cortical areas. Monitored anesthesia care (MAC) is a dominant anesthetic approach for awake craniotomy; however. it is associated with inherent challenges such as desaturation and hypercapnia. which may lead to various complications. https://www.njmaq.com/product-category/art-by-era/